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49ers vs Cardinals asks a simple question: How big is the gap?

49ers vs Cardinals asks a simple question: How big is the gap?

The San Francisco 49ers host the Arizona Cardinals at Levi's Stadium on Sept. 27 and USA TODAY's NFL experts have locked in their picks against the spread for the action.
SB NationSB Nation
Brock Purdy bails out the 49ers’ defense in a shootout win over the Cardinals

Brock Purdy bails out the 49ers’ defense in a shootout win over the Cardinals

The 49ers were decimated by injuries, but held on with a home win.
AP NewsAP News
Purdy throws 4 TD passes to lead the injury-depleted 49ers to a 36-30 win vs. the Cardinals

Purdy throws 4 TD passes to lead the injury-depleted 49ers to a 36-30 win vs. the Cardinals

Brock Purdy threw four touchdown passes with the first coming on a trick play and the injury-depleted San Francisco 49ers held on for a 36-30 victory over the Arizona Cardinals
Niners WireNiners Wire
Notes and observations from wild 49ers Week 3 win over Cardinals

Notes and observations from wild 49ers Week 3 win over Cardinals

It wasn't easy, but the San Francisco 49ers found a way to beat the Arizona Cardinals in Week 3. Here's our notebook from the game.
USA TodayUSA Today
Super Bowl 61 odds as favorite Rams prepare for 'Sunday Night Football' test

Super Bowl 61 odds as favorite Rams prepare for 'Sunday Night Football' test

The Los Angeles Rams remain the favorite to win Super Bowl 61. Who represents their top competition entering NFL Week 3?
SB NationSB Nation
3 quick takeaways from 49ers narrow win over Cardinals: Health is becoming a problem

3 quick takeaways from 49ers narrow win over Cardinals: Health is becoming a problem

The 49ers got a scare, but the offense led the way to a win.
SB NationSB Nation
49ers numbers to know: The Cardinals have a long NFC West streak on the line

49ers numbers to know: The Cardinals have a long NFC West streak on the line

Plus, the lack of 49ers pass rush
USA TodayUSA Today
What NFL games are on today? Week 3 TV channels, Sunday schedule, results

What NFL games are on today? Week 3 TV channels, Sunday schedule, results

The NFL season is off to a wild start. Here's how you can watch all of the Sunday action in Week 3.
SB NationSB Nation
Patriots rooting guide for NFL Week 3

Patriots rooting guide for NFL Week 3

Rooting information, kickoff times, TV schedule and more for NFL Week 3.
SB NationSB Nation
49ers vs. Cardinals predictions: How creative will Raheem Morris get?

49ers vs. Cardinals predictions: How creative will Raheem Morris get?

We make 3 predictions for the 49ers Week 3 game against the Cardinals
Arizona RepublicArizona Republic
Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

The Arizona Cardinals are looking to get right against the San Francisco 49ers in Week 3, after a demoralizing blowout loss to the Seattle Seahawks.
Niners WireNiners Wire
George Kittle credits one key factor in 49ers' hot 2-0 start

George Kittle credits one key factor in 49ers' hot 2-0 start

The 49ers retained a lot of key offensive personnel that helped them cruise to a 2-0 record to start 2026.