New Proteomic Technique Unveils Blood-Brain Barrier Pathways, Enhancing Drug Delivery Prospects
A team led by Jiefu Li at the Howard Hughes Medical Institute has developed a proteomic profiling method to identify proteins involved in the blood-brain barrier (BBB) transport processes. This technique, which works in vivo, allows researchers to track changes in the brain's vasculature over time. By understanding the molecular targets that regulate the BBB, the study opens new possibilities for drug delivery to the brain. The research, published in Science, highlights the potential for this method to be applied across different organs and species, providing a comprehensive understanding of vascular functions. 
