Modafinil Use in Seniors: Considerations and Alternatives
Modafinil, known as Provigil, is a wakefulness-promoting agent prescribed for conditions like narcolepsy and sleep apnea-related sleepiness. It is sometimes used off-label for fatigue in seniors, but requires careful consideration due to age-related changes in drug metabolism and potential side effects. Seniors often face polypharmacy, increasing the risk of drug interactions. Modafinil can raise blood pressure and heart rate, posing risks for those with cardiovascular issues. Alternatives like optimizing CPAP therapy, reviewing current medications, and improving sleep hygiene are recommended before considering modafinil.