Study Reveals Solriamfetol as Effective Treatment for Early-Morning Worker Fatigue
A recent study has identified Solriamfetol, a drug sold under the brand name Sunosi, as an effective treatment for fatigue among early-morning workers. Conducted by Dr. Charles A. Czeisler and his team at Mass General Brigham, the study focused on individuals who start work between 3 a.m. and 7 a.m., a group previously overlooked in clinical trials. These workers often experience fatigue due to waking up at their body's biological low point, which can lead to increased risks of cardiovascular disease, road accidents, and chronic fatigue. The study involved 78 participants who were given either Solriamfetol or a placebo over four weeks. Results showed that those taking Solriamfetol stayed awake an average of 12.5 minutes longer than before treatment, compared to a 3.1-minute improvement in the placebo group. This significant difference highlights the drug's potential to improve alertness and performance during early shifts.