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AI Virtual Cell Predicts Personalized Breast Cancer Treatments Using Protein Dynamics

AI Virtual Cell Predicts Personalized Breast Cancer Treatments Using Protein Dynamics

A new AI tool named ProteinTalks has been developed to predict the effectiveness of drugs against cancer cells, identify new drug combinations, and pinpoint proteins linked to drug resistance. This AI virtual cell utilizes protein dynamics by tracking how protein levels shift over time in response to treatment. Researchers captured over 38 million protein measurements from 18 breast cancer cell lines, observing their responses to 63 FDA-approved anticancer drugs and 59 two-drug combinations at various time points (before treatment, 6, 24, and 48 hours). ProteinTalks was trained on this time-resolved dataset, allowing it to learn the dynamic changes in protein levels as drugs take effect. The tool demonstrated superior performance compared to existing AI models based on gene activity and traditional machine-learning methods in predicting drug responses.
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Joaquin Duato Assumes Dual Role as Chairman and CEO of Johnson Johnson, Succeeding Alex Gorsky

Joaquin Duato Assumes Dual Role as Chairman and CEO of Johnson Johnson, Succeeding Alex Gorsky

Joaquin Duato Assumes Dual Role as Chairman and CEO of Johnson Johnson, Succeeding Alex Gorsky
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FIA President Mohammed Ben Sulayem Advocates for Spain to Host Two Formula 1 Races Annually

FIA President Mohammed Ben Sulayem Advocates for Spain to Host Two Formula 1 Races Annually

FIA President Mohammed Ben Sulayem Advocates for Spain to Host Two Formula 1 Races Annually
AP NewsAP News
Antonelli wins first Formula 1 race in Madrid in 45 years after unlucky break for pole-sitter Norris

Antonelli wins first Formula 1 race in Madrid in 45 years after unlucky break for pole-sitter Norris

Kimi Antonelli has taken advantage of Lando Norris' mishaps to win the Spanish Grand Prix in Formula 1’s return to Madrid, increasing his lead in the drivers’ standings
SB NationSB Nation
Player Ratings: Real Madrid 4–1 Rayo Vallecano

Player Ratings: Real Madrid 4–1 Rayo Vallecano

Real Madrid beat Rayo Vallecano 4–1 at the Bernabéu, with Kylian Mbappé delivering two goals and an assist, Álvaro Carreras making an electric start, and Arda Güler producing a spectacular cameo off the bench. The scoreline was convincing, though Rayo’s second-half improvement ensured Thibaut Courtois still had plenty of work to do. Thibaut Courtois — […]
Cincinnati EnquirerCincinnati Enquirer
Bengals vs. Buccaneers live updates: Start time, TV channel for NFL Week 1 game

Bengals vs. Buccaneers live updates: Start time, TV channel for NFL Week 1 game

The Cincinnati Bengals host the Tampa Bay Buccaneers in Week 1 at Paycor Stadium. Follow along for live updates and analysis.
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Antonelli wins 1st Formula 1 race in Madrid in 45 years after unlucky break for pole-sitter Norris

Antonelli wins 1st Formula 1 race in Madrid in 45 years after unlucky break for pole-sitter Norris

Kimi Antonelli has taken advantage of Lando Norris' mishaps to win the Spanish Grand Prix in Formula 1’s return to Madrid, increasing his lead in the drivers’ standings
VarietyVariety
Toronto Title ‘Sisters,’ Starring Spain’s Elena Anaya and Emma Suarez, Forces a Family to Visit Fears and Taboos

Toronto Title ‘Sisters,’ Starring Spain’s Elena Anaya and Emma Suarez, Forces a Family to Visit Fears and Taboos

“Sisters” (“Hermanas”) will have its world premiere in the Discovery section of the Toronto International Film Festival, running September 10-20. Written and directed by Ione Hernández Sáenz (“1% Schizophrenia”) and starring Elena Anaya (“The Skin I Live In,” “Room in Rome”) and Emma Suárez (“Julieta,” “The Next Skin”), the Spanish film is an intergenerational family […]
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Antonelli still fastest in Madrid ahead of qualifying for F1's Spanish GP as Hamilton crashes

Antonelli still fastest in Madrid ahead of qualifying for F1's Spanish GP as Hamilton crashes

Kimi Antonelli has stayed on top at the new Madring track by setting the fastest time in practice and establishing himself as the driver to beat ahead of the decisive qualifying session for the inaugural Spanish Grand Prix in Madrid
SB NationSB Nation
DAILY THREAD | Sep 12, 2026

DAILY THREAD | Sep 12, 2026

The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Gameday!! Rayo at the Bernabeu. If […]
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Javier Bardem Expresses Gratitude to U.S. While Affirming Strong Spanish Cultural Identity

Javier Bardem Expresses Gratitude to U.S. While Affirming Strong Spanish Cultural Identity

Javier Bardem Expresses Gratitude to U.S. While Affirming Strong Spanish Cultural Identity
SB NationSB Nation
Real Madrid vs Rayo Vallecano, 2026 La Liga: Predicted lineups

Real Madrid vs Rayo Vallecano, 2026 La Liga: Predicted lineups

Real Madrid host Rayo Vallecano in what should be a manageable game and a decent opportunity for José Mourinho to make some rotations, as he admitted during the pre-match press conference. PREDICTED LINEUPS Real Madrid predicted XI: Courtois; Dumfries, Konaté, Huijsen, Cucurella; Camavinga, Bernardo Silva; Güler, Bellingham, Vinicius; Mbappé. Rayo Vallecano predicted XI: Cárdenas; Ratiu, […]