Experts Highlight Complex Link Between Vitamin B12 and Cancer Risk
Recent discussions among experts have brought attention to the complex relationship between vitamin B12 and cancer risk. Vitamin B12, also known as cobalamin, is essential for producing red blood cells, maintaining nervous system function, and ensuring accurate DNA replication. While it is naturally found in animal products and fortified foods, certain groups such as vegans, older adults, and individuals with specific gut conditions may require supplements. Concerns have arisen regarding high levels of B12 intake and its potential link to cancer. A 2025 study from Vietnam suggested a U-shaped relationship between B12 intake and cancer risk, indicating that both low and high intakes could be associated with increased risk. However, the study could not establish a causal relationship. Observational research has also hinted at a slight increase in lung cancer risk with long-term, high-dose B6 and B12 supplementation, particularly among men and smokers.