Organoids and New Methodologies Transform Drug Discovery Landscape
The field of drug discovery is experiencing a significant transformation with the adoption of New Approach Methodologies (NAMs), including organoids, organs-on-chip, and engineered 3D tissues. These technologies are moving from proof-of-concept to everyday use in drug screening, discovery, and safety studies. The FDA Modernization Act 2.0 and other regulatory frameworks are accelerating the shift towards non-animal models. This research topic brings together leaders from academia, industry, and regulatory agencies to discuss the current state and future directions of NAMs in drug discovery.