University of Kent Researchers Identify Skincare Compound with Potential to Combat Drug-Resistant Bacteria
Researchers at the University of Kent, in collaboration with University College London, have discovered that madecassic acid, a compound derived from the plant Centella asiatica, exhibits strong antibacterial properties. This compound, commonly used in Korean skincare, has shown potential in fighting antibiotic-resistant bacteria, a significant global health threat. The study utilized computer-based screening and laboratory experiments to demonstrate that madecassic acid can inhibit the growth of antibiotic-resistant E. coli by targeting the cytochrome bd complex, a protein system crucial for bacterial respiration. This discovery is particularly important as antimicrobial resistance is projected to cause millions of deaths in the coming decades. The research highlights the potential of plant-based chemicals in developing new antibiotics.