UIC Researchers Develop Anti-Cancer Therapy Inspired by Bacteria in Tumors
Researchers at the University of Illinois Chicago have developed a novel anti-cancer therapy inspired by bacteria found in tumors. This therapy, when combined with radiation, has shown significant efficacy in animal models of prostate cancer by effectively halting tumor growth. The therapy utilizes a peptide called aurB, derived from a bacterial protein, which disrupts energy production in tumor cells' mitochondria, cutting off their fuel supply. This approach targets the mitochondria, which are crucial for cell survival and are often altered in cancer cells to support rapid growth. The research, published in Signal Transduction and Targeted Therapy, highlights the potential of bacterial proteins as sources for anti-tumor agents.