Africa CDC Investigates Mystery Illness in Burundi Resulting in Multiple Deaths
A mystery illness has emerged in Burundi, resulting in the deaths of at least five individuals and affecting 35 others since March 30. The Africa Centres for Disease Control and Prevention (Africa CDC) reports a case-fatality rate of 14%. Symptoms of the illness include fever, vomiting, diarrhea, headache, and dark urine, with severe cases showing neurological symptoms, anemia, jaundice, and difficulty breathing. Despite extensive testing, samples from patients have tested negative for over 200 pathogens, including Ebola, Marburg virus, and yellow fever. Public health officials are investigating potential zoonotic transmission, conducting animal testing on pigs and cattle to determine if the illness may have originated from animals. The World Health Organization (WHO) is assisting Burundi's health ministry in enhancing disease surveillance, field investigation, clinical care, laboratory diagnosis, and infection prevention and control.