Protein Restriction Research Highlights FGF21 Hormone's Role in Longevity and Metabolism
Recent livestock research, as covered by Science Daily, indicates that restricting dietary protein can significantly impact longevity and metabolic health, primarily through the hormone FGF21 (fibroblast growth factor 21). When protein intake decreases, the liver produces more FGF21, which in turn can increase energy expenditure, improve blood sugar regulation, and reduce inflammation. This hormone acts as an endocrine signal, linking the liver and brain to regulate metabolism and feeding behavior during periods of protein restriction. The body appears to interpret protein availability as crucial information, with FGF21 signaling a coordinated response that alters appetite, energy use, growth, and overall metabolism. This effect has been observed across various animal species, and researchers are exploring whether this coordinated response explains the striking longevity effects seen in laboratory animals. The research challenges the notion that more protein is always better, suggesting a complex interplay...
