Neuraly, Inc. Initiates Phase 2 Trial of Pegsebrenatide for Progressive Multiple Sclerosis
Neuraly, Inc., a subsidiary of D&D Pharmatech, has commenced a Phase 2 trial to evaluate pegsebrenatide (NLY01) for treating progressive multiple sclerosis (MS). This trial, led by Dr. Ellen Mowry from Johns Hopkins University, involves 120 patients and aims to assess the drug's impact on neurodegeneration. Pegsebrenatide is a GLP-1 receptor agonist designed to modulate neuroinflammatory pathways and protect neurons. Previous studies in Parkinson's disease patients showed promising results, supporting its potential as a disease-modifying therapy for neurodegenerative conditions.