Guidance Issued for Urgent Care Assessment of Hyperemesis Gravidarum Labs
New guidance, including the 2024 RCOG Green-top Guideline No. 69, outlines critical laboratory findings in hyperemesis gravidarum (HG) that necessitate urgent hospital review. These include severe electrolyte disturbances, rising creatinine levels, hypoglycemia, ketoacidosis, or liver abnormalities accompanied by low platelets or impaired clotting. Specific warning signs for immediate assessment are potassium levels below 2.5 mmol/L, sodium below 125 mmol/L, or the presence of neurological symptoms. The guidance emphasizes that a clinical diagnosis of HG does not require abnormal blood tests, as severe nausea and vomiting before 16 weeks, inability to eat or drink, and significant daily activity restriction can establish the diagnosis. Initial testing typically includes sodium, potassium, chloride, bicarbonate, urea or BUN, creatinine, glucose, and a full blood count, with liver tests, magnesium, and phosphate added for severe or atypical cases. The guideline explicitly advises against using ketonuria as a...