NetraAI Platform Enhances Clinical Trials with Explainable AI for Depression Treatment
The NetraAI platform, an explainable AI system, is revolutionizing clinical trial enrichment by identifying treatment-responsive patient subpopulations. This platform addresses the challenges of high-dimensional interactions in small, heterogeneous clinical trial datasets. NetraAI's architecture includes a dynamical systems-based clustering engine and an iterative feature learning process, allowing it to model placebo responses as informative variables. This approach enables the identification of clinically meaningful subpopulations, enhancing the precision of drug efficacy analysis. In a Phase II depression trial, NetraAI successfully identified a psychiatric scale model that enriched for responders with over 80% true positives, demonstrating its potential to improve clinical trial outcomes. 
