Harvard Study Identifies Metabolites for Potential Diabetes and Obesity Treatments
A research team at Harvard University, supported by the São Paulo Research Foundation, has identified a collection of metabolites that travel from the intestine to the liver and then to the heart, potentially influencing metabolic processes related to obesity and type 2 diabetes. The study, published in the journal Cell Metabolism, highlights how these metabolites, derived from the gut microbiome, can affect insulin response and liver metabolism. The research involved analyzing blood samples from mice with varying susceptibilities to obesity and diabetes, revealing significant differences in metabolite profiles based on genetic and environmental factors. The findings suggest that these metabolites could play a crucial role in mediating conditions like obesity and diabetes.