Global Experts Urge Action Against Rising Antifungal Drug Resistance
Infectious disease experts worldwide are raising alarms over a growing resistance to antifungal drugs, which they describe as a 'silent surge.' This resistance is particularly concerning with pathogens like Candida auris and azole-resistant Aspergillus, which are increasingly found in intensive care units and communities. The experts, led by Paul Verweij from Radboud University Medical Centre, have published a five-step plan in Nature Medicine to address this issue. Their plan aims to influence the World Health Organization's upcoming update to its Global Action Plan on Antimicrobial Resistance (AMR). The proposed measures include raising awareness, improving surveillance, enhancing infection prevention and control, optimizing current antifungal therapies, and increasing investment in new diagnostics and medicines. The experts emphasize the need for support in low- and middle-income countries, where the impact of drug-resistant fungi is particularly severe.