New Single-Cell Platform Enhances Understanding of Immune Signaling
Researchers have developed a new single-cell sequencing platform, CIPHER-seq, which simultaneously measures RNA and proteins within immune cells. This advancement provides a more comprehensive view of immune cell behavior by capturing both genetic instructions and functional protein output. The platform addresses the limitations of RNA-only approaches, which can be misleading, especially in cytokine signaling. Developed by the University of Miami Miller School of Medicine and collaborators, CIPHER-seq offers insights into immune responses, potentially aiding in the design of better immunotherapies and predicting patient outcomes.