MIT Study Explores Enhanced Mucosal Immunity for Injectable Polio Vaccines
Researchers at the Massachusetts Institute of Technology (MIT) have developed an experimental adjuvant that could enhance mucosal immunity when used with injectable polio vaccines. The study, published in Science Advances, suggests that the adjuvant, known as Am80, can be delivered using lipid nanoparticles to stimulate immune cells to target the mucosal lining of the intestine. This approach aims to combine the safety of the injectable polio vaccine with the mucosal immunity typically provided by the oral polio vaccine, which some countries have stopped using due to a small risk of infection.