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49ers News: Let Brandin Cook(s)

49ers News: Let Brandin Cook(s)

Your daily San Francisco 49ers news for Saturday, October 3rd, 2026

4 matchups to watch when Broncos face 49ers in Week 4

4 matchups to watch when Broncos face 49ers in Week 4

The Denver Broncos will need to get the best of these matchups if they want to hand the San Francisco 49ers their first loss in Week 4.

Broncos' 53-man roster for Sunday's game vs. 49ers

Broncos' 53-man roster for Sunday's game vs. 49ers

Here's a look at the Broncos' 53-man roster going into today's game against the 49ers.

Bo Nix and Brock Purdy share mutual respect going into Week 4 showdown

Bo Nix and Brock Purdy share mutual respect going into Week 4 showdown

"The appreciation level is really high, and we respect each other and we know what each other goes through," Bo Nix said of Brock Purdy.

NFL picks: Who the experts predict to win in the Broncos-49ers game

NFL picks: Who the experts predict to win in the Broncos-49ers game

Who will win when the undefeated 49ers host the Broncos on Sunday? NFL experts make their game picks.

3 keys to victory for the Broncos against the 49ers

3 keys to victory for the Broncos against the 49ers

The Denver Broncos can hand the San Francisco 49ers their first loss of the season if they follow these three keys to victory.

Can the 49ers wear down the Broncos in 90-degree weather?

Can the 49ers wear down the Broncos in 90-degree weather?

There will be high temperatures in Santa Clara this Sunday. Can the 49ers make the Broncos pay?

Broncos will have extreme heat to contend with vs. 49ers

Broncos will have extreme heat to contend with vs. 49ers

The Denver Broncos had a rough time at it on the road in Kansas City when the area was experiencing a hot and humid weather event. Now in Week 4 they’ll be on the road again to play the San Francisco 49ers and it may end up being the hottest temperature in that stadium’s history […]

Broncos vs. 49ers: 3 Players to Watch in Week 4

Broncos vs. 49ers: 3 Players to Watch in Week 4

In order to defeat the San Francisco 49ers on Sunday, these three players need to perform well.

Broncos defense faces another major challenge in San Francisco offense

Broncos defense faces another major challenge in San Francisco offense

Denver’s defense faces another major test as the 49ers bring a balanced and talented offense to the Week 4 matchup.

Broncos have 3 core players developed by the 49ers

Broncos have 3 core players developed by the 49ers

Three core players on the Broncos' roster were drafted and developed by the 49ers before landing in Denver.

NFL picks and predictions: Broncos vs. 49ers and the rest of Week 4

NFL picks and predictions: Broncos vs. 49ers and the rest of Week 4

Mile High Report’s Christopher Hart predicts the straight-up winners for every Week 4 matchup of the 2026 season.