Explore

USA TodayUSA Today
49ers vs Cardinals asks a simple question: How big is the gap?

49ers vs Cardinals asks a simple question: How big is the gap?

The San Francisco 49ers host the Arizona Cardinals at Levi's Stadium on Sept. 27 and USA TODAY's NFL experts have locked in their picks against the spread for the action.
Arizona RepublicArizona Republic
Cardinals vs 49ers live score updates from NFL Week 3 game today

Cardinals vs 49ers live score updates from NFL Week 3 game today

What's the 49ers vs Cardinals score? Follow our NFL Week 3 updates for latest news, notes, analysis, highlights from San Francisco vs Arizona game.
USA TodayUSA Today
Mike Evans plans to play

Mike Evans plans to play

Mike Evans optimistic about facing Arizona
SB NationSB Nation
3 quick takeaways from 49ers narrow win over Cardinals: Health is becoming a problem

3 quick takeaways from 49ers narrow win over Cardinals: Health is becoming a problem

The 49ers got a scare, but the offense led the way to a win.
Cardinals WireCardinals Wire
What TV channel is Cardinals vs. 49er on today? Time, TV schedule for NFL Week 3

What TV channel is Cardinals vs. 49er on today? Time, TV schedule for NFL Week 3

The Arizona Cardinals and San Francisco 49ers face off in Week 3. Here's where to watch and start time.
Sportsbook WireSportsbook Wire
Arizona Cardinals at San Francisco 49ers odds, picks and predictions

Arizona Cardinals at San Francisco 49ers odds, picks and predictions

The Arizona Cardinals and San Francisco 49ers clash in Week 2 in Santa Clara, California, at 4:05 p.m. ET.
Niners WireNiners Wire
8 thoughts, takeaways from 49ers' thrilling Week 3 win over Cardinals

8 thoughts, takeaways from 49ers' thrilling Week 3 win over Cardinals

There was a lot to take out of the San Francisco 49ers' tense Week 3 win over the Arizona Cardinals. Here are the takeaways.
USA TodayUSA Today
Christian McCaffrey goes over 100 total yards vs. Cardinals

Christian McCaffrey goes over 100 total yards vs. Cardinals

Christian McCaffrey keeps chugging along, totaling 116 yards and a score in Week 3 against Arizona.
SB NationSB Nation
BTSC late games and Sunday Night Football thread

BTSC late games and Sunday Night Football thread

Chat about the rest of the Sunday slate here at Behind the Steel Curtain.
SB NationSB Nation
49ers vs. Cardinals predictions: How creative will Raheem Morris get?

49ers vs. Cardinals predictions: How creative will Raheem Morris get?

We make 3 predictions for the 49ers Week 3 game against the Cardinals
Arizona RepublicArizona Republic
Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

The Arizona Cardinals are looking to get right against the San Francisco 49ers in Week 3, after a demoralizing blowout loss to the Seattle Seahawks.
SB NationSB Nation
49ers News: Kyle’s scheme will hopefully be Raising Arizona’s miscommunications on defense

49ers News: Kyle’s scheme will hopefully be Raising Arizona’s miscommunications on defense

Your daily San Francisco 49ers news for Friday, September 25th, 2026