Time-Restricted Eating Shows Modest Weight Loss Without Calorie Restriction, Johns Hopkins Study Finds
A Johns Hopkins Medicine study investigated the effects of time-restricted eating (TRE) on weight loss and eating habits in adults with obesity and prediabetes or diet-controlled type 2 diabetes. The study, known as TRIM and published in the journal Obesity, analyzed 39 adults over 12 weeks. Nineteen participants were assigned to eat within a 10-hour window, while 20 spread their meals over 16 hours. Both groups consumed an adapted DASH diet, with calories personalized to maintain their starting weight, and all meals were prepared by research dietitians. The 10-hour group lost a median of 2.7% of body weight, while the 16-hour group lost a median of 2.5%, a difference of only 0.3 kg. The study found no significant differences between the groups in appetite hormones, inflammation markers, or eating-behavior scores. Daisy Duan, M.D., an assistant professor of medicine at Johns Hopkins and the study's primary author, noted that while the 10-hour group lost weight and improved eating habits without calorie res...