GLP-1 Medications Require Special Considerations for Adults Over 65, UNC Health Geriatrician Advises
Adults aged 65 and older considering GLP-1 medications like Ozempic and Zepbound for weight management and diabetes control need to be aware of specific considerations, according to UNC Health geriatrician John Batsis, MD. While these medications offer significant benefits in weight loss and blood sugar regulation, most initial trials were conducted on adults younger than 65, meaning there is less specific data for older populations. Dr. Batsis highlights that while the benefits of weight loss and improved blood sugar control remain, older adults face different risks. These include increased susceptibility to gastrointestinal side effects like nausea and constipation, which can lead to dehydration. Additionally, rapid weight loss in older adults can result in a more pronounced loss of muscle and bone mass, potentially increasing the risk of osteoporosis, frailty, falls, and permanent disability. He advises a 'low and slow' approach to dosing and emphasizes the importance of a balanced diet, regular exercis...