HSS Study Highlights Efficacy of Non-Opioid Pain Relief in Orthopedic Surgery
A study conducted by the Hospital for Special Surgery (HSS) has evaluated the effectiveness of a new non-opioid pain reliever, suzetrigine, in postoperative orthopedic surgery patients. The medication, approved by the FDA in January 2025, targets pain signals on nerves outside the brain, offering a novel approach to pain management. The study involved 103 patients, with 92.2% tolerating the drug well. Suzetrigine presents a promising alternative to opioids, particularly for patients with contraindications to opioid use. The research is part of HSS's ongoing efforts to advance non-opioid pain management options and improve patient outcomes. 
