Texas A Researchers Develop Nasal Spray to Combat Memory Loss in Aging Mice
Researchers at Texas A&M University have developed a nasal spray that has shown promise in reducing brain inflammation and restoring memory function in aging mice. The spray targets 'neuroinflammaging,' a condition characterized by chronic stress in the aging brain, which is linked to cognitive decline and neurological disorders such as Alzheimer's disease. The treatment involves the use of extracellular vesicles (EVs) derived from human stem cells, which are packed with proteins and genetic instructions. These EVs are delivered intranasally, allowing them to reach the brain more directly. In the study, 18-month-old mice, equivalent to humans in their late 50s to 60s, received two doses of the spray. The treated mice showed improved performance in tasks measuring object recognition and spatial memory, indicating a reduction in brain inflammation. 
