Mayo Clinic Advances Personalized Treatment for Meningioma Patients with Precision Oncology
Mayo Clinic researchers have published a comprehensive review in Nature Reviews Clinical Oncology, highlighting significant advancements in the diagnosis and treatment of meningiomas, the most common primary brain tumors. This review emphasizes a shift towards personalized patient care, integrating molecular diagnostics, advanced imaging, and clinical insights. Meningiomas account for about 37% of all central nervous system tumors, presenting diverse biological behaviors and anatomical challenges. Traditional methods, primarily based on histopathological examination, often fall short in predicting tumor recurrence or stratifying patient risk. The review advocates for a molecular and imaging-driven approach to enhance diagnostic accuracy and optimize therapeutic interventions. Recent molecular classification advances allow for better prediction of tumor progression and response to therapy, with genetic and epigenetic profiling playing a crucial role. Advanced imaging techniques, such as PET/MRI, enable earl... 
