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Actor Luis Guzmán to Co-Host 17th Annual Cristian Rivera Foundation Celebrity Gala in NYC

Actor Luis Guzmán to Co-Host 17th Annual Cristian Rivera Foundation Celebrity Gala in NYC

Actor Luis Guzmán is set to co-host the 17th Annual Cristian Rivera Foundation Celebrity Gala at Cipriani Wall Street in New York City. He will be joined by Kenan Thompson and Darlene Rodriguez for the event, which begins at 6:00 p.m. with a red-carpet reception. The gala includes hors d’oeuvres, a five-hour open bar, dinner, an award ceremony, and a video presentation. Live and silent auctions featuring unique items and experiences will also be part of the evening. The event aims to unite celebrities, supporters of the Cristian Rivera Foundation, and D.I.P.G. Warriors to raise funds for Diffuse Intrinsic Pontine Glioma (D.I.P.G.) research and family support. The foundation is a significant financial supporter of D.I.P.G. research, having donated over four million dollars to date.

Mount Sinai Health System Seeks Bioinformatician III for AI Human Health Research

Mount Sinai Health System Seeks Bioinformatician III for AI Human Health Research

The Mount Sinai Health System's Artificial Intelligence and Human Health Department is actively seeking a Bioinformatician III to join its expanding genomics and precision medicine research program. This role is designed for a highly motivated genetic epidemiologist or statistical geneticist who will be instrumental in leading and supporting analyses of extensive genomic, proteomic, multi-omics, and longitudinal clinical datasets. The successful candidate will apply advanced statistical genetics, bioinformatics, machine learning, and AI methodologies to uncover the biological underpinnings of complex and rare diseases. This position offers a unique opportunity to spearhead independent research projects, contribute to high-impact publications and grant applications, and collaborate within a multidisciplinary team at the forefront of human genetics and precision medicine. The role requires a minimum of six years of experience and proficiency in various computational tools and environments, including R, Pytho...

Pharmacogenomics Advances Personalized Medicine by Linking Genetics to Drug Response

Pharmacogenomics Advances Personalized Medicine by Linking Genetics to Drug Response

Pharmacogenomics is an evolving field that studies how an individual's genetic makeup influences their response to medications. This scientific discipline aims to move healthcare beyond a trial-and-error approach by using genetic information to predict how a patient will react to specific drugs. By analyzing genetic variations, doctors can potentially identify more suitable medications and dosages, thereby reducing adverse side effects and improving treatment efficacy. This approach is particularly beneficial in areas such as antidepressant prescriptions, cardiovascular treatments, and cancer therapies. While not every prescription requires or benefits from pharmacogenomic testing, it offers a more personalized method for healthcare providers to tailor medical treatments to individual patient characteristics. The integration of genomic real-world data, which links genetic information with clinical outcomes from routine care, is crucial for advancing this field. This data allows researchers to connect DNA v...

Nvidia's out-of-hour shares fall as firm probes CEO Jensen Huang

Nvidia's out-of-hour shares fall as firm probes CEO Jensen Huang

By Heekyong Yang, Kyu-seok Shim and Tom Westbrook SEOUL/SYDNEY, Nov 9 (Reuters) - Nvidia shares fell in out-of-hours trading on Monday after an internal investigation into whether CEO Jensen Huang had been targeted by a foreign intelligence effort put his future at the AI chipmaker under scrutiny.

Cleveland Clinic Study Reveals Gene-Silencing Therapy's Dual Impact on High Cholesterol and Triglycerides

Cleveland Clinic Study Reveals Gene-Silencing Therapy's Dual Impact on High Cholesterol and Triglycerides

A new study led by Cleveland Clinic has demonstrated that a single dose of ARO-DIMER-PA, a gene-silencing medication, significantly reduced both 'bad' cholesterol (LDL-C) and triglycerides in patients diagnosed with mixed hyperlipidemia. The findings were presented at the American Heart Association’s Scientific Sessions 2026 in Chicago. Dr. Luke Laffin, study author and medical director of the Cleveland Clinic Coordinating Center for Clinical Research, highlighted that this is the first time a single drug has successfully blocked two separate disease pathways in the liver simultaneously. The medication, a small interfering RNA (siRNA), targets and silences both APOC3 and PCSK9 genes, which are involved in lipid metabolism. While other siRNA medications typically target only one gene, ARO-DIMER-PA's dual action led to dose-dependent reductions in PCSK9 and APOC3 proteins by 50-89% and 43-95% respectively. Consequently, LDL-C was reduced by 26-65% and triglycerides by 56-78%. The drug was generally well-tole...

ANCO and MOASC Host Precision Oncology Symposium to Advance Personalized Cancer Care

ANCO and MOASC Host Precision Oncology Symposium to Advance Personalized Cancer Care

The Association of Northern California Oncologists (ANCO) and the Medical Oncology Association of Southern California (MOASC) are organizing a symposium focused on precision oncology. This event aims to translate molecular tumor profiling and advancements in targeted therapies into personalized cancer care. The multidisciplinary scientific program will cover precision medicine across various cancer types, including gastrointestinal, genitourinary, lung, breast, and gynecologic cancers. Key educational objectives include integrating germline and somatic genomic findings, understanding tumor-agnostic FDA approvals, and making biomarker-driven treatment decisions. The symposium also addresses challenges associated with genomic testing and emphasizes patient-centered care through collaboration with patient advocates to improve access to biomarker-driven treatments. Healthcare professionals attending can earn up to 5.75 AMA PRA Category 1 Credits™.

National Institutes of Health Study Links Anti-Scl-70 Autoantibody Changes to Lung Function Decline in Systemic Sclerosis

National Institutes of Health Study Links Anti-Scl-70 Autoantibody Changes to Lung Function Decline in Systemic Sclerosis

A study led by Dr. Eric W. Robbins, Clinical Fellow at the Critical Care Medicine and Pulmonary Branch of the National Heart, Lung, and Blood Institute, National Institutes of Health, has found a significant association between serial quantitative changes in anti-Scl-70 autoantibody levels and subsequent lung function decline in systemic sclerosis (SSc). The research, presented at ACR Convergence 2026, utilized a luciferase immunoprecipitation systems (LIPS) assay to evaluate patients from the multicenter CONQUER registry. The findings indicate that early increases in anti-Scl-70 levels consistently correlated with worsening pulmonary function. This suggests that tracking the trajectory of autoantibody levels over time can provide prognostic information beyond a single baseline measurement, offering a more dynamic understanding of disease progression in SSc patients. The study aims to identify patients at greater risk for future pulmonary worsening by using serial antibody measurements as a dynamic biomark...

‘Gangs of London’ Director Kim Hong-sun Shoots Korean Martial Arts Action Film ‘The Hit List’ With Jung Woo-sung, ‘Squid Game’ Star Wi Ha-jun

‘Gangs of London’ Director Kim Hong-sun Shoots Korean Martial Arts Action Film ‘The Hit List’ With Jung Woo-sung, ‘Squid Game’ Star Wi Ha-jun

Kim Hong-sun, the Korean director of “Project Wolf Hunting” and Season 3 of British crime drama “Gangs of London,” is shooting “The Hit List,” a martial arts revenge actioner set during Korea’s Joseon era, with Jung Woo-sung and “Squid Game” star Wi Ha-jun. “The Hit List” adapts a Kakao webtoon that has drawn more than […]

South Korean corporate reforms hit rough patch as Samsung digs in

South Korean corporate reforms hit rough patch as Samsung digs in

By Gregor Stuart Hunter and Heekyong Yang SINGAPORE/SEOUL, Nov 6 (Reuters) - Global investors are pressing South Korea's biggest conglomerates to speed up corporate governance reforms, saying progress has been uneven, with gains in financials offset by resistance among large chaebol affiliates.

GeneDx and Mirum Pharmaceuticals Partner to Offer No-Cost Genetic Testing for Rare Diseases

GeneDx and Mirum Pharmaceuticals Partner to Offer No-Cost Genetic Testing for Rare Diseases

GeneDx and Mirum Pharmaceuticals have announced a collaboration to provide no-cost exome testing for eligible patients suffering from specific rare conditions. These conditions include cholestasis, early-onset cataracts, and peroxisomal biogenesis disorder–Zellweger spectrum disorders (PBD-ZSD). The initiative aims to identify underlying genetic causes to facilitate accurate diagnoses and inform clinical treatment decisions. Through this program, eligible patients will receive GeneDx's ExomeDx™ testing, which offers proband, duo, or trio testing options. Clinicians involved will be provided with a comprehensive clinical report that includes expert interpretation of the results, and GeneDx will also offer post-test genetic counseling to support families and healthcare providers.

South Korean Auteur Lee Explores Mass Layoffs and Societal Impact in New Film

South Korean Auteur Lee Explores Mass Layoffs and Societal Impact in New Film

South Korean Auteur Lee Explores Mass Layoffs and Societal Impact in New Film

Peace Corps Volunteer Gloria Mamokhin Pioneered Speech Therapy in Korea, Transforming Healthcare

Peace Corps Volunteer Gloria Mamokhin Pioneered Speech Therapy in Korea, Transforming Healthcare

In 1969, Peace Corps Volunteer Gloria Mamokhin (née Gloria Levin), a speech therapist, arrived in Korea and was instrumental in establishing the country's first speech pathology centers. At the time, Korea had no such facilities. Mamokhin, serving from 1969 to 1971 (K-7), was encouraged by Peace Corps Korea Director Kevin O'Donnell to pursue her specialty. She collaborated with Seoul National University (SNU) Hospital and Severance Hospital, demonstrating her ability to teach a deaf child to speak, which led to the establishment of clinics. Mamokhin trained eight women at both institutions, laying the groundwork for a new field of healthcare in Korea. Her work extended to treating Korean veterans of the Vietnam War suffering from aphasia. The impact of her pioneering efforts is evident today, with Korea now boasting 4,500 speech pathologists, numerous university communication majors, and a national Speech-Language & Hearing Association.