Stanford Researchers Identify Brain Circuit Responsible for Chronic Pain
Researchers at Stanford University have mapped a specific neural circuit responsible for chronic pain, offering new insights into potential treatments for the 60 million Americans affected by persistent pain. The study, published in Nature, reveals a circuit that activates after injury or inflammation, causing the brain to misinterpret gentle touch as painful. By silencing this circuit, researchers were able to eliminate chronic hypersensitivity while preserving acute pain responses. This discovery separates acute pain, a vital survival signal, from chronic pain, which can be targeted individually.