UBC Okanagan Researchers Decode Cancer-Fighting Plant Compound, Paving Way for Sustainable Production
Researchers at UBC Okanagan have made a significant breakthrough in understanding how plants produce mitraphylline, a rare compound with potential cancer-fighting properties. Mitraphylline is part of a unique class of plant chemicals known as spirooxindole alkaloids, which are noted for their complex structures and biological effects, including anti-inflammatory and anti-tumor activities. The research team, led by Dr. Thu-Thuy Dang, identified two critical enzymes that are essential in the production of mitraphylline. This discovery answers longstanding questions about the molecular processes plants use to create these compounds and opens new avenues for replicating them in laboratories. The research was a collaborative effort with the University of Florida and received funding from several Canadian and U.S. institutions.