Traditional Chinese Medicine Shows Promise in Treating Neurodegenerative Disorders
A recent review has explored the potential of Traditional Chinese Medicine (TCM) in treating neurodegenerative diseases (NDDs) such as Alzheimer's, Parkinson's, and Huntington's diseases. The study highlights cellular senescence as a key factor in the pathogenesis of these disorders, characterized by irreversible cell cycle arrest and the secretion of pro-inflammatory cytokines. TCM-derived compounds, including ginsenosides, ginkgo biloba extract, and curcumin, have shown promise in modulating cellular senescence and alleviating neurodegeneration. The review examines the molecular signaling pathways linking cellular senescence to NDDs and discusses the translational potential of these natural compounds for clinical application.