Study Finds Low-Calorie Diet and Exercise Induce Diabetes Remission in Younger Adults
A clinical trial conducted in Canada and the UK has demonstrated that a low-calorie diet combined with supervised exercise can lead to remission in over half of younger adults diagnosed with early-onset type 2 diabetes (EOT2D). EOT2D is characterized by diagnosis at 45 years or younger and typically follows a more aggressive course with a higher risk of complications. The study, known as RESET for Remission, involved participants aged 18 to 45 with type 2 diabetes diagnosed within the previous six years and living with obesity. The intervention group followed an 800-900 kilocalorie per day diet for 12 weeks, gradually transitioning to a weight maintenance diet, alongside supervised aerobic and resistance exercise. Results showed that 54% of participants in the intervention group achieved remission, defined as HbA1c below 6.5% without glucose-lowering medication for at least 12 weeks, compared to 4% in the control group. The intervention also led to significant reductions in body fat, preservation of muscle...
