Tadalafil, an Erectile Dysfunction Drug, Explored for Longevity and Cardiovascular Benefits
Tadalafil, commonly known by its brand name Cialis, an erectile dysfunction drug, is gaining attention in biohacking and wellness circles for potential longevity benefits beyond its approved uses. Online clinics and influential figures, including Stanford neuroscientist Andrew Huberman and biohacker Bryan Johnson, are promoting tadalafil as an 'all-purpose longevity drug' that may offer advantages for cardiovascular health, brain function, and athletic performance. While the drug is not approved by regulatory bodies for preventing heart attack, stroke, or extending life, observational studies have shown associations between tadalafil use and lower rates of cardiovascular mortality and dementia. For instance, an analysis of over 8,000 men taking tadalafil indicated a 55% lower rate of cardiovascular-related deaths and a 44% lower overall mortality rate. Another study involving over half a million patients suggested a 32% lower risk of dementia. These findings, though observational, are considered 'consisten... 
