ROBOKOP v1.0 System Enhances Biomedical Knowledge Graph Exploration and Reasoning
The ROBOKOP (Reasoning Over Biomedical Objects linked in Knowledge Oriented Pathways) v1.0 system has been released, offering an open-source, modular, biomedical knowledge graph (KG)-based platform. This system integrates and harmonizes over 30 knowledge sources, containing approximately 10 million nodes and 130 million edges, to facilitate the exploration of relationships between biomedical entities. Key components include the ROBOKOP KG, a user interface (UI), and supporting tools. The Operational Routine for the Ingest and Output of Networks (ORION) pipeline standardizes and integrates these diverse knowledge sources using the Biolink Model's universal KG schema. Users can query the system through a Question-Builder tool, which translates natural-language questions into machine-readable queries, or via Cypher and TRAPI endpoints for more complex inquiries. The system provides ranked answers, with detailed provenance and supporting evidence for each assertion, including publications and source informatio...