Canadian Researchers Report Possible HIV Cure Following Bone Marrow Transplant
In a groundbreaking development, researchers at the University Health Network (UHN) in Toronto have reported a case of sustained HIV remission following a bone marrow transplant. The patient, referred to as the Toronto patient, had been living with HIV for 27 years and developed acute myelogenous leukemia, necessitating the transplant. The procedure used donor stem cells with a rare genetic mutation that provides resistance to HIV. Post-transplant, the patient's HIV levels progressively declined, and antiretroviral therapy was discontinued in July 2025. As of April 2026, HIV remains undetectable in the patient, marking a potential cure. This case, presented at the Canadian Association of HIV Research Conference, highlights the collaborative efforts of clinicians and researchers across multiple institutions in Toronto. 
