Scientists Develop Transcriptomic Clock to Predict Biological Age and Mortality Risk
Researchers from Harvard Medical School and Tohoku University have developed a 'transcriptomic clock' that measures biological age based on cell function rather than chronological age. This tool analyzes gene expression profiles, or transcriptomes, across various tissues in four species: mice, rats, macaques, and humans. By identifying which genes are activated in response to aging or interventions that affect lifespan, the clock provides a detailed measure of aging. The study, published in Nature, suggests that this method could improve the accuracy of predicting disease and mortality risk, potentially aiding in the development of anti-aging therapies.