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City of Hope Study Links Sugar Consumption During Antibiotic Treatment to Gut Microbiome Disruption

City of Hope Study Links Sugar Consumption During Antibiotic Treatment to Gut Microbiome Disruption

A new study conducted by researchers at City of Hope suggests that consuming less sugar during antibiotic treatment may help protect the gut microbiome. The study, published in 'Nature', followed blood cancer patients undergoing allogeneic hematopoietic cell transplant, a population highly susceptible to severe gut microbiome disruption. Researchers analyzed over 9,400 meals and 1,000 stool samples from 173 hospitalized patients, linking sugar-rich foods to greater antibiotic-related microbiome disruption. Co-senior author Marcel van den Brink, M.D., Ph.D., stated that antibiotics disrupt the diversity of gut bacteria, which are crucial for immune system support. The study found that patients who consumed more sweets while taking antibiotics experienced a significant loss of microbiome diversity, with aggressive microbes like Enterococcus crowding out other bacterial strains. This effect was particularly pronounced with broad-spectrum antibiotics and high-sugar intake, leading to a 24% drop in bacterial di...
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NYU Langone Health Study Reveals Sugar Amplifies Antibiotic Damage to Gut Microbiome

NYU Langone Health Study Reveals Sugar Amplifies Antibiotic Damage to Gut Microbiome

A new study led by researchers from NYU Langone Health, City of Hope, and Memorial Sloan Kettering has found that consuming sugar while taking antibiotics can worsen the damage to the gut's bacterial community. The research, published in the journal Nature, tracked the diets of 173 hospitalized cancer patients, analyzing 9,419 meals and their corresponding gut microbiome changes. The study observed an additional 21% reduction in alpha diversity, a measure of beneficial bacterial species variety, for every 100 grams of sugar consumed within 48 hours before antibiotic treatment. This combination of a sugary diet and antibiotics was also linked to an increase in harmful bacterial species like Enterococcus faecium, which is associated with difficult-to-treat infections. Experiments in mice further confirmed this pattern, showing a significant increase in Enterococcus populations when exposed to antibiotics and dietary sucrose.
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Study Reveals Sugar Amplifies Antibiotic Damage to Gut Microbiome in Cancer Patients

Study Reveals Sugar Amplifies Antibiotic Damage to Gut Microbiome in Cancer Patients

A new study, led by researchers from NYU Langone Health, City of Hope, and Memorial Sloan Kettering, indicates that consuming sweets while taking antibiotics can worsen the damage these drugs inflict on the gut's bacterial community. The research, published in the journal Nature, tracked the dietary intake of 173 hospitalized cancer patients, analyzing over 9,000 meals and daily gut microbiome samples. It found that for every 100 grams of sugar consumed in the 48 hours before antibiotic treatment, there was an additional 21% reduction in alpha diversity, a measure of beneficial bacterial species. This combination of a sugary diet and antibiotics also led to a proliferation of harmful bacterial species like Enterococcus faecium, which is associated with difficult-to-treat infections. Experiments in mice corroborated these findings, showing a significant increase in Enterococcus populations when exposed to antibiotics and dietary sucrose. The study highlights the vulnerability of the gut microbiome, especial...
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Sugary Foods Combined with Antibiotics May Harm Gut Bacteria, Study Finds

Sugary Foods Combined with Antibiotics May Harm Gut Bacteria, Study Finds

New research indicates that consuming sugary foods while taking antibiotics can significantly damage the gut microbiome, potentially leaving individuals vulnerable to dangerous infections. The study, published in the journal Nature, analyzed data from over 1,000 stool samples of 173 hospitalized cancer patients who were on sustained antibiotic regimens and consumed hospital-prepared meals. Researchers observed that for every 3.5-ounce increase in sweets consumption during antibiotic treatment, the diversity of a patient’s gut microbiome decreased by approximately 24%. This reduction in diversity was linked to an expansion of opportunistic bacteria, such as Enterococcus faecium, which can cause severe infections like sepsis, especially in immunocompromised individuals. The study, led by scientists at Memorial Sloan Kettering Cancer Center and NYU Langone Health, also found that patients who ate more sugar had a 12% higher risk of dying after stem cell transplants.
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Sugar-Rich Diets Exacerbate Antibiotic-Induced Gut Microbiome Disruption, Study Finds

Sugar-Rich Diets Exacerbate Antibiotic-Induced Gut Microbiome Disruption, Study Finds

A study published in Nature reveals that sugar-rich foods can worsen the disruption of the gut microbiome caused by antibiotics. The research, conducted on adult allo-HCT recipients at Memorial Sloan Kettering Cancer Center in New York between 2017 and 2022, involved monitoring dietary intake and microbiome changes. Patients were asked to record their consumption of each meal item, and this data was linked to detailed food classifications. The study found that the interaction between sugar intake and antibiotic exposure significantly impacted microbial diversity. Specifically, a 100g increase in 'sweets' (dehydrated weight) exacerbated the negative effects of antibiotics on the gut microbiome. This finding was consistent across different conditioning intensities for transplant patients.
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Dietary Sugar Intake Linked to Gut Microbiome Disruption During Antibiotic Treatment in Cancer Patients

Dietary Sugar Intake Linked to Gut Microbiome Disruption During Antibiotic Treatment in Cancer Patients

A study conducted by Jonathan Peled at the Memorial Sloan Kettering Cancer Center in New York and his colleagues has revealed that consuming high-sugar foods while taking antibiotics can significantly reduce the diversity of the gut microbiome. The research, involving 158 blood cancer patients undergoing chemotherapy and antibiotic treatment, meticulously tracked dietary intake and changes in gut bacteria. The findings indicate that for every 100-gram increase in high-sugar food or drink consumption during antibiotic treatment, the drop in total bacterial diversity was, on average, 24% greater. This combination also led to an increase in potentially pathogenic bacteria, such as Enterococcus faecium, which can cause hospital-acquired infections. The study suggests that antibiotics disrupt the gut's bacterial balance, and sugar acts as 'rocket fuel' for the remaining, often less beneficial, strains.
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Dry skin and achy joints? It may not be an omega-3 deficiency

Dry skin and achy joints? It may not be an omega-3 deficiency

Determining whether someone needs more omega-3 is not as simple as looking out for dry skin or achy joints. Here's what to know.
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Black Nile Rewrites L.A. Jazz Narrative, Embracing TikTok for New Generation

Black Nile Rewrites L.A. Jazz Narrative, Embracing TikTok for New Generation

Black Nile Rewrites L.A. Jazz Narrative, Embracing TikTok for New Generation
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A look at Cubs postseason history

A look at Cubs postseason history

The Cubs have a long, but not very storied, postseason history. Here are all the numbers.
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Austin Reaves ‘happy to be back’ with Lakers after ‘weird’ contract negotiations

Austin Reaves ‘happy to be back’ with Lakers after ‘weird’ contract negotiations

Reaves is ecstatic to have a new deal and just focus on playing basketball again
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Kawhi Leonard excited to be back in Toronto, move past NBA investigation

Kawhi Leonard excited to be back in Toronto, move past NBA investigation

By Field Level Media Sep 28 (Field Level Media) - Embroiled in a high-profile contract-based controversy, which led to an investigation that lasted a full year, Kawhi Leonard is searching for a path forward in the same way he has sliced through defenses throughout his career.
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Every quote from LeBron James’ first media availability as a Sixer

Every quote from LeBron James’ first media availability as a Sixer

LeBron James has spoken to the Philadelphia media for the first time. Here is every notable quote from his availability.