GRAIL's Galleri Test Shows Significant Increase in Cancer Detection at ASCO Meeting
GRAIL, Inc. presented the results of its PATHFINDER 2 study at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, showcasing the effectiveness of the Galleri Multi-Cancer Early Detection (MCED) test. The study involved 35,878 participants aged 50 and older, with no clinical suspicion of cancer, across the U.S. and Canada. The Galleri test, when added to standard cancer screenings, increased cancer detection by 6.5 times. Notably, 71% of the new cancers detected were in stages I-III, where treatment is more likely to be successful. The test demonstrated a positive predictive value of 60.3% and a specificity of 99.6%, indicating a low false-positive rate. The Galleri test also accurately identified the cancer signal origin 91.3% of the time, facilitating efficient diagnostic workups.