California Faces Record High Tuberculosis Outbreaks, Surpassing National Trends
California is experiencing a significant surge in Tuberculosis (TB) cases, with the state reporting over 2,150 cases in 2025, marking the highest number in 12 years. This figure is nearly double the national incidence rate, with California reporting 5.4 cases per 100,000 people compared to the national average of three per 100,000. The U.S. Centers for Disease Control and Prevention (CDC) has identified 50 large TB outbreaks in the U.S. between 2017 and 2023, with 79% of these cases involving U.S.-born individuals. The outbreaks are primarily linked to family or social networks and congregate settings. Factors contributing to the rise in TB cases include housing insecurity, substance use, immigration, and incarceration, which are prevalent in California.