University of Iowa Researchers Demonstrate Noninvasive Brain Stimulation Targeting Deep Brain Regions
Neuroscientists at the University of Iowa Health Care have successfully demonstrated that noninvasive transcranial magnetic stimulation (TMS) can alter the activity of the hippocampus, a deep brain region involved in emotion and memory. This study, published in Nature Communications, highlights the potential of TMS to engage and modulate hippocampal activity without the need for surgery or medication. The research involved eight neurosurgical patients with electrodes implanted in their hippocampus, allowing for precise measurement of brain activity changes. By personalizing the stimulation site based on each patient's unique brain connectivity, the researchers were able to significantly enhance the neuromodulation effect. This approach could pave the way for safer, noninvasive treatments for conditions like Alzheimer's disease, depression, and PTSD.