U.S. Newborn Congenital Syphilis Rates Soar Nearly Sixfold from 2012 to 2022, Disproportionately Affecting Native American Babies
Congenital syphilis rates among U.S. newborns increased by nearly six times between 2012 and 2022, according to a study published in Clinical Infectious Diseases. The research, conducted by Johns Hopkins University, analyzed hospital records from 14.6 million birth hospitalizations, identifying an estimated 6,560 newborns diagnosed with congenital syphilis. The rate rose from 16.0 per 100,000 birth hospitalizations in 2012 to 94.7 per 100,000 in 2022. This increase was observed across all racial and ethnic groups, income levels, and hospital settings. The most significant rise was among American Indian and Alaska Native newborns, where rates surged 21.5-fold, from 22.7 to 486.0 per 100,000 birth hospitalizations. In 2022, Hispanic newborns accounted for the largest number of congenital syphilis hospitalizations, followed by Black and White newborns. Geographically, the West had the highest rates, though over half of the hospitalizations occurred in the South.