Mayo Clinic Researchers Publish Key Studies on Liver Disease, IBS, and AI-Assisted Ultrasound
Mayo Clinic research teams recently published three significant studies in academic journals. One study, conducted in collaboration with Virginia Tech, identified five distinct subtypes of metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease. By analyzing health record data from nearly 5,000 MASLD patients, researchers used a computational model to categorize these subtypes, revealing varying risks for non-liver complications such as kidney failure, depression, sleep apnea, and heart disease. Another study, co-authored by Dr. Gianrico Farrugia, Mayo Clinic's president and CEO, investigated the role of gut bacteria in constipation-dominant irritable bowel syndrome (IBS-C). This research, published in the Proceedings of the National Academy of Sciences, found that lower levels of hypoxanthine and butyrate, produced by gut bacteria, impact intestinal food movement. The third study, published in JAMA Cardiology, tested an AI tool designed to ass...