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Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

Can the Arizona Cardinals upset the 49ers? Breaking down the matchup

The Arizona Cardinals are looking to get right against the San Francisco 49ers in Week 3, after a demoralizing blowout loss to the Seattle Seahawks.
AP NewsAP News
49ers coach Kyle Shanahan faces another disciple in game against Cardinals coach Mike LaFleur

49ers coach Kyle Shanahan faces another disciple in game against Cardinals coach Mike LaFleur

San Francisco 49ers coach Kyle Shanahan said he might appreciate one day how many assistants that used to work under him have become head coaches in the NFL
SB NationSB Nation
Arizona Cardinals defense still dealing with some injuries ahead of matchup with Niners

Arizona Cardinals defense still dealing with some injuries ahead of matchup with Niners

Check in on the Friday Cardinals injury report.
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John Lynch on Brock Purdy: We’re just entering his prime

John Lynch on Brock Purdy: We’re just entering his prime

Is the 49ers quarterback in the midst of his prime?
Cardinals WireCardinals Wire
49ers injury report: 8 sit out Wednesday

49ers injury report: 8 sit out Wednesday

See which 49ers players didn't practice or were limited on Wednesday.
Niners WireNiners Wire
49ers 1st Week 3 practice report isn't all bad news with 8 players out

49ers 1st Week 3 practice report isn't all bad news with 8 players out

There are eight players listed on the San Francisco 49ers' first practice report of Week 3, but it isn't as bad as it looks on paper.
SB NationSB Nation
49ers News: Kyle’s scheme will hopefully be Raising Arizona’s miscommunications on defense

49ers News: Kyle’s scheme will hopefully be Raising Arizona’s miscommunications on defense

Your daily San Francisco 49ers news for Friday, September 25th, 2026
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49ers News: Welcome to the Bay, Brandin Cooks!

49ers News: Welcome to the Bay, Brandin Cooks!

Your daily San Francisco 49ers news for Wednesday, September 23rd, 2026
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Pattern Degradations and Bad Dresses; Miami Dolphins stumble against 49ers

Pattern Degradations and Bad Dresses; Miami Dolphins stumble against 49ers

Dolphins continue slow start in week two.
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Miami Dolphins fan confidence: Week 3 survey

Miami Dolphins fan confidence: Week 3 survey

Are the Dolphins headed in the right direction? We want to know your confidence in the team.
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Sean McVay admits travel mistake, takes blame for Week 1 approach

Sean McVay admits travel mistake, takes blame for Week 1 approach

The Rams head coach took blame for the team’s travel plans in Week 1.
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49ers report card: The offense is exceeding expectations because of Brock Purdy

49ers report card: The offense is exceeding expectations because of Brock Purdy

Passing out grades from the 49ers’ Week 2 wins on both sides of the ball