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How the Denver Broncos can defeat the San Francisco 49ers

How the Denver Broncos can defeat the San Francisco 49ers

Here are three things the Denver Broncos must accomplish on Sunday to defeat the San Francisco 49ers.

Broncos vs. 49ers: 3 Things to Watch in Week 4

Broncos vs. 49ers: 3 Things to Watch in Week 4

The Denver Broncos head on the road to take on the undefeated San Francisco 49ers. Here are three storylines I’ll be watching closely.

Broncos defense bracing for tough matchup versus versatile 49ers offense

Broncos defense bracing for tough matchup versus versatile 49ers offense

The Denver Broncos will have a big challenge going up the well-coached and versatile offense of the San Francisco 49ers.

Broncos at 49ers: Predictions, picks and odds for NFL Week 4 game

Broncos at 49ers: Predictions, picks and odds for NFL Week 4 game

The San Francisco 49ers host the Denver Broncos at Levi's Stadium on Oct. 4 and USA TODAY's NFL experts have locked in their picks for the action.

Pro Picks: Patrick Mahomes and the Chiefs will hand the Raiders their first loss

Pro Picks: Patrick Mahomes and the Chiefs will hand the Raiders their first loss

Only five NFL teams remain unbeaten and two of them face off in Week 4

Dre Greenlaw gets first crack at his old team in Week 4 vs. Broncos

Dre Greenlaw gets first crack at his old team in Week 4 vs. Broncos

Dre Greenlaw spent one season with the Broncos in 2025 before being released.

Vance Joseph sees Christian McCaffrey as being a problem on third downs

Vance Joseph sees Christian McCaffrey as being a problem on third downs

The San Francisco 49ers present a unique challenge for the Denver Broncos defense and it is on defensive coordinator Vance Joseph to figure out how to overcome that challenge. One of the keys to that offense is how they use running back Christian McCaffrey and when Joseph was asked about him he identified the biggest […]

NFL Week 4 game picks: Odds and expert predictions for every matchup

NFL Week 4 game picks: Odds and expert predictions for every matchup

The NFL schedule is loaded with important matchups in Week 4. Here's a breakdown of expert picks, predictions and the latest odds for every game.

49ers News: We’re on to Denver

49ers News: We’re on to Denver

Your daily San Francisco 49ers news for Wednesday, September 30th, 2026

NFL Week 4 Power Rankings: Biggest September Surprises

NFL Week 4 Power Rankings: Biggest September Surprises

Week 4’s WCG NFL Power Rankings are here! After another unpredictable week, there were plenty of shakeups. @AaronLemingNFL has details here.

The Denver Broncos need to start scoring early this week

The Denver Broncos need to start scoring early this week

The San Francisco 49ers pose the toughest challenge to date for the Denver Broncos.

The 49ers’ injuries aren’t sustainable, but Brock Purdy might make them survivable

The 49ers’ injuries aren’t sustainable, but Brock Purdy might make them survivable

Purdy is playing at an MVP level, and is getting help from an oft-maligned area of the 49ers’ roster.