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Bills vs Lions prediction, keys to historic Highmark Stadium opener

Bills vs Lions prediction, keys to historic Highmark Stadium opener

The Bills officially open Highmark Stadium Thursday night in their home opener against the Lions. Here is Sal Maiorana's preview of the game.
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Bills news: Previewing the Lions

Bills news: Previewing the Lions

Points should be plentiful when Josh Allen and the Bills host Jared Goff and the Lions on Thursday Night Football.
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5 Qs Lions vs. Bills preview: Have Buffalo’s playmakers leveled up Josh Allen?

5 Qs Lions vs. Bills preview: Have Buffalo’s playmakers leveled up Josh Allen?

Here’s our preview with Buffalo Rumblings about this Week 2 matchup between the Detroit Lions and Buffalo Bills.
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5 Detroit Lions to watch at the Buffalo Bills

5 Detroit Lions to watch at the Buffalo Bills

Can Buffalo’s defense slow down a high-powered Detroit offense?
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The Honolulu Blueprint: 4 predictions for a Lions victory over the Bills in Week 2

The Honolulu Blueprint: 4 predictions for a Lions victory over the Bills in Week 2

Predicting what the Detroit Lions will do to earn a victory over the Buffalo Bills in Week 2 of the 2026 season.
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Bills at Texans Week 1 snap counts: Tight ends take over, defense logs 79 snaps

Bills at Texans Week 1 snap counts: Tight ends take over, defense logs 79 snaps

Buffalo leaned heavily on multiple tight end packages while several defensive starters rarely left the field
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Detroit Lions updated depth chart: Week 2 at Bills

Detroit Lions updated depth chart: Week 2 at Bills

An updated look at the 2026 Detroit Lions’ depth chart ahead of their Week 2 game vs. the Buffalo Bills.
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Survey: Will the Lions beat the Bills in Week 2?

Survey: Will the Lions beat the Bills in Week 2?

Checking in with Detroit Lions fans in our latest SB Nation Reacts surveys.
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Detroit Lions vs. Buffalo Bills preview, prediction: On Paper

Detroit Lions vs. Buffalo Bills preview, prediction: On Paper

Detroit Lions vs. Buffalo Bills preview and prediction using heavy data sets.
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Bills news: What to know ahead of Week 2 vs. Detroit Lions

Bills news: What to know ahead of Week 2 vs. Detroit Lions

Everything you need to know as Josh Allen and the Bills look to start the season 2-0 for the sixth time in eight years.
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Bills set to open new stadium hosting the Lions in a prime-time matchup

Bills set to open new stadium hosting the Lions in a prime-time matchup

Josh Allen is more focused on the outcome than the setting as the Buffalo Bills prepare to play the first regular-season game at their new Highmark Stadium by hosting the Detroit Lions on Thursday night
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Lions Week 2 preview: Breaking down Bills’ offensive, defensive schemes

Lions Week 2 preview: Breaking down Bills’ offensive, defensive schemes

Breaking down the offensive and defensive schemes of the Buffalo Bills, the Detroit Lions’ Week 2 opponent.