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Indianapolis Colts at Pittsburgh Steelers odds, picks and predictions

Indianapolis Colts at Pittsburgh Steelers odds, picks and predictions

The Indianapolis Colts visit the Pittsburgh Steelers Sunday for a 1 p.m. ET kickoff from Acrisure Stadium in Pittsburgh, Pennsylvania.

Steelers CB Jamel Dean ruled OUT vs. Colts

Steelers CB Jamel Dean ruled OUT vs. Colts

Steelers rule CB Jamel Dean out vs. Colts.

NFL experts predict winner of Colts v. Steelers Week 5 game

NFL experts predict winner of Colts v. Steelers Week 5 game

Let's take a look at who several NFL experts are predicting to win the Colts vs. Steelers Week 5 matchup.

NFL picks and predictions: Broncos vs. Chargers and the rest of Week 5

NFL picks and predictions: Broncos vs. Chargers and the rest of Week 5

Mile High Report’s Christopher Hart predicts the straight-up winners for every Week 5 matchup of the 2026 season.

McCarthy is staying the course as uneven Steelers try to steady themselves vs. the improving Colts

McCarthy is staying the course as uneven Steelers try to steady themselves vs. the improving Colts

The Pittsburgh Steelers will try to put an uneven opening month of the season behind them when Indianapolis visits

Steelers-Colts preview: What Indianapolis will throw at Pittsburgh?

Steelers-Colts preview: What Indianapolis will throw at Pittsburgh?

Both of these teams are 2-2 and hoping for a win to remain in their respective division races.

RB Rico Dowdle returns to Steelers practice ahead of Colts matchup

RB Rico Dowdle returns to Steelers practice ahead of Colts matchup

The Steelers running back gets closer to a return, but Pittsburgh is down two top defensive backs ahead of Week 5.

Steelers' offensive keys to victory for Week 5 game vs. Colts

Steelers' offensive keys to victory for Week 5 game vs. Colts

Here's a look at three offensive keys to victory for the Pittsburgh Steelers' Week 5 matchup against the Indianapolis Colts.

Arizona Republic

NFL Week 5 predictions, picks, win probabilities for games this week

NFL Week 5 predictions, picks, win probabilities for games this week

NFL Week 5 picks, predictions, win probabilities for Buccaneers vs Cowboys, Eagles vs Jaguars, Bengals vs Dolphins, Raiders vs Patriots, more games.

NFL picks against the spread for Week 5 from our expert staff

NFL picks against the spread for Week 5 from our expert staff

Our panel of experts is back to give you picks against the spread for every game on a loaded Week 5 slate.

NFL Week 5 predictions by Microsoft Copilot AI for every game

NFL Week 5 predictions by Microsoft Copilot AI for every game

USA TODAY Sports is having Microsoft Copilot AI pick the results of every game for the 2026 NFL season. Here are the chatbot's Week 5 picks.

Steelers vs. Colts Week 5, Wednesday injury report: What fans should know

Steelers vs. Colts Week 5, Wednesday injury report: What fans should know

Here is Wednesday's Week 5 injury report for the Pittsburgh Steelers against the Indianapolis Colts.