Explore

SB NationSB Nation
The 49ers are running into the stingiest defense in the NFL

The 49ers are running into the stingiest defense in the NFL

Three numbers to watch heading into Week 5 between the 49ers and Seahawks
Seahawks WireSeahawks Wire
3 things to watch for in Seahawks’ Week 5 matchup vs. 49ers

3 things to watch for in Seahawks’ Week 5 matchup vs. 49ers

Injuries, MVP-caliber players and defensive objectives will be on center stage in Week 5 and dictate how the Seahawks’ matchup against the 49ers goes.
AP NewsAP News
The 49ers travel to face the Seahawks in their 1st meeting since last season's playoff loss

The 49ers travel to face the Seahawks in their 1st meeting since last season's playoff loss

Games between the San Francisco 49ers and Seattle Seahawks are typically intense with the two rivals often competing for NFC West supremacy
SB NationSB Nation
‘As good as it gets’ – 49ers’ ascending position group faces its toughest test

‘As good as it gets’ – 49ers’ ascending position group faces its toughest test

The 49ers have made huge strides up front this season, but they face a different level of challenge in Week 5.
SB NationSB Nation
5 takeaways from coordinators: Mykel Williams gives the 49ers ‘a lot of juice’

5 takeaways from coordinators: Mykel Williams gives the 49ers ‘a lot of juice’

The biggest takeaways from Week 5 of the San Francisco 49ers coordinators
SB NationSB Nation
NFL predictions: Jaxon Smith-Njigba will dominate for Seahawks vs. 49ers

NFL predictions: Jaxon Smith-Njigba will dominate for Seahawks vs. 49ers

Seattle’s star could go supernova against the 49ers. Again.
SB NationSB Nation
Seahawks vs. 49ers, Week 5 preview: The keys to Seattle beating San Francisco once again

Seahawks vs. 49ers, Week 5 preview: The keys to Seattle beating San Francisco once again

Seattle must close the gaps, pressure Brock Purdy and stay disciplined to hand San Francisco its first loss.
Niners WireNiners Wire
NFL Week 5 television maps: San Francisco 49ers vs. Seattle Seahawks

NFL Week 5 television maps: San Francisco 49ers vs. Seattle Seahawks

The San Francisco 49ers and Seattle Seahawks are ready to do battle this weekend, and this broadcast map will tell you if you can see this game on TV.
Arizona RepublicArizona Republic
Seahawks vs 49ers predictions, picks, odds for NFL Week 5 game Sunday

Seahawks vs 49ers predictions, picks, odds for NFL Week 5 game Sunday

San Francisco 49ers vs Seattle Seahawks picks, predictions, odds, win probabilities for NFL Week 5 Sunday game on Oct. 11, 2026. Who will win game?
Niners WireNiners Wire
49ers vs. Seahawks: Every Week 5 injury update for San Francisco

49ers vs. Seahawks: Every Week 5 injury update for San Francisco

Injuries are once again a huge story for the 4-0 San Francisco 49ers. We have all the updates leading up to a Week 5 game vs. the Seattle Seahawks.
SB NationSB Nation
49ers-Seahawks: 3 major differences from last year’s roster

49ers-Seahawks: 3 major differences from last year’s roster

The 49ers overhauled their roster at wide receiver, plus they have some key pieces returning who didn’t play late against the Seahawks last season
Niners WireNiners Wire
Best and worst PFF grades from 49ers' Week 4 victory over Broncos

Best and worst PFF grades from 49ers' Week 4 victory over Broncos

The San Francisco 49ers beat the Denver Broncos on Sunday, moving to 4-0 in 2026. Here were their best and worst PFF grades from their victory.