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AP News
The 49ers dial up a hook-and-ladder play to open scoring against the Cardinals
The San Francisco 49ers went deep in the playbook to open up the scoring against the Arizona Cardinals
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USA Today
49ers vs Cardinals asks a simple question: How big is the gap?
The San Francisco 49ers host the Arizona Cardinals at Levi's Stadium on Sept. 27 and USA TODAY's NFL experts have locked in their picks against the spread for the action.
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For the Win
When is Nick Bosa coming back to the 49ers?
Here's what we know about when Nick Bosa might come back to the 49ers as he deals with a calf injury.
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SB Nation
49ers numbers to know: The Cardinals have a long NFC West streak on the line
Plus, the lack of 49ers pass rush
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Niners Wire
George Kittle credits one key factor in 49ers' hot 2-0 start
The 49ers retained a lot of key offensive personnel that helped them cruise to a 2-0 record to start 2026.
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AP News
49ers coach Kyle Shanahan faces another disciple in game against Cardinals coach Mike LaFleur
San Francisco 49ers coach Kyle Shanahan said he might appreciate one day how many assistants that used to work under him have become head coaches in the NFL
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Arizona Republic
Can the Arizona Cardinals upset the 49ers? Breaking down the matchup
The Arizona Cardinals are looking to get right against the San Francisco 49ers in Week 3, after a demoralizing blowout loss to the Seattle Seahawks.
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Niners Wire
49ers GM John Lynch gives update on Brandin Cooks could see the field
Don't expect Brandin Cooks to suit up for the 49ers anytime soon despite him recently signing with the team.
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Niners Wire
49ers head coach, offensive star explain what new WR brings to SF
Brandin Cooks already has a glowing endorsement from his head coach and running back.
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SB Nation
49ers News: Kyle’s scheme will hopefully be Raising Arizona’s miscommunications on defense
Your daily San Francisco 49ers news for Friday, September 25th, 2026
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AP News
Brock Purdy elevates his game even more to start season for the 49ers
Brock Purdy has produced at a high level ever since bursting on the scene as a seventh-round rookie in 2022 who went on a deep playoff run with the San Francisco 49ers
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Niners Wire
49ers All-Pro won't let Rams use travel as excuse for Week 1 beatdown
George Kittle wants everyone to know the 49ers took down the Rams because they were the better team.
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