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3 winners, 8 losers from Detroit Lions’ loss to Buffalo Bills

3 winners, 8 losers from Detroit Lions’ loss to Buffalo Bills

The Detroit Lions got thrashed by the Buffalo Bills in primetime. What led to this failure?
USA TodayUSA Today
Josh Allen wins, Lions' secondary loses (again) as Bills roll

Josh Allen wins, Lions' secondary loses (again) as Bills roll

The Bills opened their new stadium in style on Thursday Night Football as Josh Allen showed MVP form against an abysmal Lions' defense.
SB NationSB Nation
5 takeaways from Detroit Lions’ 41-31 loss against Buffalo Bills

5 takeaways from Detroit Lions’ 41-31 loss against Buffalo Bills

5 takeaways from the Detroit Lions’ 41-31 loss against the Buffalo Bills on Thursday Night Football.
SB NationSB Nation
The Honolulu Blueprint: 4 predictions for a Lions victory over the Bills in Week 2

The Honolulu Blueprint: 4 predictions for a Lions victory over the Bills in Week 2

Predicting what the Detroit Lions will do to earn a victory over the Buffalo Bills in Week 2 of the 2026 season.
Detroit Free PressDetroit Free Press
Dan Campbell 'nervous' about Detroit Lions' latest injury at safety

Dan Campbell 'nervous' about Detroit Lions' latest injury at safety

Already down starters Kerby Joseph and Brian Branch, the Lions could lose safety Avonte Maddox to a foot injury.
Rochester Democrat and ChronicleRochester Democrat and Chronicle
Bills vs Lions prediction, keys to historic Highmark Stadium opener

Bills vs Lions prediction, keys to historic Highmark Stadium opener

The Bills officially open Highmark Stadium Thursday night in their home opener against the Lions. Here is Sal Maiorana's preview of the game.
Detroit Free PressDetroit Free Press
Lions' slimmer margin for error is clear after Bills stampede defense

Lions' slimmer margin for error is clear after Bills stampede defense

When it mattered, the Detroit Lions defense was almost always in the wrong place at the wrong time against the Buffalo Bills on Thursday.
SB NationSB Nation
Buffalo Bills vs. Detroit Lions, Week 2: 5 questions for primetime bout

Buffalo Bills vs. Detroit Lions, Week 2: 5 questions for primetime bout

Five questions about the Detroit Lions ahead of their Week 2 heavyweight bout with the Buffalo Bills
USA TodayUSA Today
Bills vs Lions spread predictions, odds for NFL Week 2 Thursday Night Football

Bills vs Lions spread predictions, odds for NFL Week 2 Thursday Night Football

The Buffalo Bills host the Detroit Lions at Highmark Stadium on Sept. 17 and USA TODAY's NFL experts have locked in their picks against the spread for the action.
SB NationSB Nation
Detroit Lions updated depth chart: Week 2 at Bills

Detroit Lions updated depth chart: Week 2 at Bills

An updated look at the 2026 Detroit Lions’ depth chart ahead of their Week 2 game vs. the Buffalo Bills.
Detroit Free PressDetroit Free Press
Kelvin Sheppard, Brad Holmes biggest losers from Lions' loss to Bills

Kelvin Sheppard, Brad Holmes biggest losers from Lions' loss to Bills

There is a lot of blame after the Detroit Lions' 41-31 loss to the Buffalo Bills on Thursday, but it starts with the defense and GM Brad Holmes.
Detroit Free PressDetroit Free Press
Lions rookie DT Gill-Howard impresses in NFL debut: 'Crazy to be here'

Lions rookie DT Gill-Howard impresses in NFL debut: 'Crazy to be here'

Skyler Gill-Howard, a 6th-round pick from Texas Tech, had 3 tackles, 2 pressures and played good run defense against the Saints for the Detroit Lions.