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Rochester Democrat and Chronicle

Bills vs Patriots prediction, key matchups in AFC East clash

Bills vs Patriots prediction, key matchups in AFC East clash

For the second week in a row, the Bills are hosting a team in desperate need of a victory. Here is Sal Maiorana's preview of the Bills-Patriots game.

Rochester Democrat and Chronicle

Bills face a shaken Drake Maye and three questions of their own

Bills face a shaken Drake Maye and three questions of their own

Drake Maye has struggled badly, but the Bills have concerns involving Christian Benford, pass protection and James Cook’s fumbling.

Patriots at Bills: Predictions, picks and odds for NFL Week 4 game

Patriots at Bills: Predictions, picks and odds for NFL Week 4 game

The Buffalo Bills host the New England Patriots at Highmark Stadium on Oct. 4 and USA TODAY's NFL experts have locked in their picks for the action.

Bills Week 4 rooting interests: Who Buffalo fans should root for

Bills Week 4 rooting interests: Who Buffalo fans should root for

One more week for strength of schedule, strength of victory, and a little AFC chaos before the rules start to change.

Allen seeks to put sloppy play behind him as Bills host turnover-prone Maye and the Patriots

Allen seeks to put sloppy play behind him as Bills host turnover-prone Maye and the Patriots

Buffalo Bills quarterback Josh Allen understands he’s got plenty to clean up after committing three turnovers in beating the Los Angeles Chargers

NFL Week 4 predictions by Microsoft Copilot AI for every game

NFL Week 4 predictions by Microsoft Copilot AI for every game

USA TODAY Sports is having Microsoft Copilot AI pick the results of every game for the 2026 NFL season. Here are the chatbot's Week 4 picks.

2026 Week 4 rooting guide for Cowboys fans

2026 Week 4 rooting guide for Cowboys fans

Hopefully this is a good week for the Cowboys.

NFL MVP power rankings Week 4: We have a new leader in the MVP race

NFL MVP power rankings Week 4: We have a new leader in the MVP race

Buffalo Bills QB Josh Allen's rough week drops him out of top spot in NFL MVP power rankings. See who took over and the latest odds entering Week 4.

Pro Picks: Patrick Mahomes and the Chiefs will hand the Raiders their first loss

Pro Picks: Patrick Mahomes and the Chiefs will hand the Raiders their first loss

Only five NFL teams remain unbeaten and two of them face off in Week 4

NFL team grades for September includes only one 'A' – and a lone 'F'

NFL team grades for September includes only one 'A' – and a lone 'F'

The first month of the 2026 NFL regular season is complete, so it's time for early grades for all 32 teams. Who earned the top mark, and who flunked?

Is there a Thursday Night Football game tonight? NFL Week 4 schedule

Is there a Thursday Night Football game tonight? NFL Week 4 schedule

The NFL regular season rolls into Week 4. Does that mean there is a Thursday Night Football game tonight? Here's what to know.

NFL quarterback rankings: Drake Maye, you (!) are the grossest QB of Week 3

NFL quarterback rankings: Drake Maye, you (!) are the grossest QB of Week 3

Our gross quarterback rankings gets a new leader, and Jalen Hurts joins the fray too.