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Broncos defense bracing for tough matchup versus versatile 49ers offense

Broncos defense bracing for tough matchup versus versatile 49ers offense

The Denver Broncos will have a big challenge going up the well-coached and versatile offense of the San Francisco 49ers.

Broncos vs. 49ers: 3 Things to Watch in Week 4

Broncos vs. 49ers: 3 Things to Watch in Week 4

The Denver Broncos head on the road to take on the undefeated San Francisco 49ers. Here are three storylines I’ll be watching closely.

Broncos at 49ers: Predictions, picks and odds for NFL Week 4 game

Broncos at 49ers: Predictions, picks and odds for NFL Week 4 game

The San Francisco 49ers host the Denver Broncos at Levi's Stadium on Oct. 4 and USA TODAY's NFL experts have locked in their picks for the action.

Dre Greenlaw gets first crack at his old team in Week 4 vs. Broncos

Dre Greenlaw gets first crack at his old team in Week 4 vs. Broncos

Dre Greenlaw spent one season with the Broncos in 2025 before being released.

The Denver Broncos need to start scoring early this week

The Denver Broncos need to start scoring early this week

The San Francisco 49ers pose the toughest challenge to date for the Denver Broncos.

How the Denver Broncos can defeat the San Francisco 49ers

How the Denver Broncos can defeat the San Francisco 49ers

Here are three things the Denver Broncos must accomplish on Sunday to defeat the San Francisco 49ers.

NFL picks and predictions: Broncos vs. 49ers and the rest of Week 4

NFL picks and predictions: Broncos vs. 49ers and the rest of Week 4

Mile High Report’s Christopher Hart predicts the straight-up winners for every Week 4 matchup of the 2026 season.

NFL Week 4 announcers assignments revealed

NFL Week 4 announcers assignments revealed

The schedule is set for Week 4 of the NFL season when it comes to what announcers will be calling each game.

49ers News: We’re on to Denver

49ers News: We’re on to Denver

Your daily San Francisco 49ers news for Wednesday, September 30th, 2026

NFL team grades for September includes only one 'A' – and a lone 'F'

NFL team grades for September includes only one 'A' – and a lone 'F'

The first month of the 2026 NFL regular season is complete, so it's time for early grades for all 32 teams. Who earned the top mark, and who flunked?

NFL Week 4 Power Rankings: Biggest September Surprises

NFL Week 4 Power Rankings: Biggest September Surprises

Week 4’s WCG NFL Power Rankings are here! After another unpredictable week, there were plenty of shakeups. @AaronLemingNFL has details here.

NFL Power Rankings Week 4: Rams haven't shown proof of concept as Super Bowl contender

NFL Power Rankings Week 4: Rams haven't shown proof of concept as Super Bowl contender

The Rams don't look like a Super Bowl team right now. More in this week's NFL Power Rankings.