Explore
USA Today
49ers vs Cardinals asks a simple question: How big is the gap?
The San Francisco 49ers host the Arizona Cardinals at Levi's Stadium on Sept. 27 and USA TODAY's NFL experts have locked in their picks against the spread for the action.
Read More
SB Nation
Brock Purdy bails out the 49ers’ defense in a shootout win over the Cardinals
The 49ers were decimated by injuries, but held on with a home win.
Read More
Sportsbook Wire
Arizona Cardinals at San Francisco 49ers odds, picks and predictions
The Arizona Cardinals and San Francisco 49ers clash in Week 2 in Santa Clara, California, at 4:05 p.m. ET.
Read More
Cardinals Wire
Cardinals vs. 49ers opponent preview: Keys, matchups, predictions
Niners Wire lead writer Kyle Madson answers questions and makes predictions about the Week 3 Cardinals-49ers game.
Read More
AP News
Receiver Mike Evans is ruled out for the 49ers with a rib injury
San Francisco 49ers receiver Mike Evans left the game against the Arizona Cardinals in the first half with a rib injury and won’t return
Read More
AP News
The 49ers dial up a hook-and-ladder play to open scoring against the Cardinals
The San Francisco 49ers went deep in the playbook to open up the scoring against the Arizona Cardinals
Read More
SB Nation
49ers vs. Cardinals: How to watch, game time, and betting odds
It’s Week 3 and the Cardinals are coming to town. Here’s everything you need to know
Read More
Cardinals Wire
49ers injury report: Mike Evans questionable vs. Cardinals
See which 49ers players won't play or might not play against the Cardinals in Week 3.
Read More
Niners Wire
6 wide receivers the 49ers could target in a trade this season
The 49ers may need to look into the trade pool to add more receivers.
Read More
Arizona Republic
Can the Arizona Cardinals upset the 49ers? Breaking down the matchup
The Arizona Cardinals are looking to get right against the San Francisco 49ers in Week 3, after a demoralizing blowout loss to the Seattle Seahawks.
Read More
AP News
49ers coach Kyle Shanahan faces another disciple in game against Cardinals coach Mike LaFleur
San Francisco 49ers coach Kyle Shanahan said he might appreciate one day how many assistants that used to work under him have become head coaches in the NFL
Read More
Niners Wire
George Kittle credits one key factor in 49ers' hot 2-0 start
The 49ers retained a lot of key offensive personnel that helped them cruise to a 2-0 record to start 2026.
Read More
